A Secret Weapon For ceesdekker
A Secret Weapon For ceesdekker
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Nanotechnology provides A variety of chances to lead to biology. Below I'll existing illustrations where by nanofabrication – a chance to make confined buildings with Proportions at will – is used to look at the biophysics of one molecules and cells. I'll existing some illustrations from our lab:
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Like a individual, I contain the biblical assignment to discover and use anything in generation for the benefit of my neighbour. I don't knowledge any conflict concerning religion and science. Quite the opposite, my faith stimulates me to complete science, for being open up-minded on the earth.’
Nanofabrication of electrodes with sub-5 nm spacing for transportation experiments on single molecules and steel clusters
We acquire level-of-care diagnostics exam of neglected tropical disorders in resource-limited configurations, determined by Crspr/Cas9 detecting of pathogen’s DNA in physique fluids.
The coiled-coil with the human Rad50 DNA fix protein contains precise segments of improved adaptability
Due to the fact 2000 he moved to solitary-molecule biophysics and nanobiology, with study from DNA supercoiling research of nucleosomes and DNA repair proteins to DNA translocation by nanopores. Recently his research has centered on learning mobile division with micro organism on chip, although his greatest desire is within the direction of noticing synthetic cells.
2000, discovery that nanotubes can carry incredible big recent densities; fixed the controversial problem of electronic transportation through DNA molecules by measurements of insulating conduct at The only molecule amount; and demonstration of the AFM method for solitary-molecule manipulation of nanotubes
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But carbon nanotubes have remained a investigate matter of significant curiosity to numerous. Certainly, the outlook on making use of carbon nanotubes to build practical equipment, in parts for example radio-frequency electronics, digital electronics and flexible electronics, continues to be vivid.
Instance (4) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is demonstrated in grey, the rim of your pore is highlighted in purple, as well as a 3D rendering from the movement on the DNA rod is shown.
2001, discovery of solitary-electron transistors at area temperature determined by nanotubes; realization of 1st logic circuits with carbon nanotube products; and discovery on the molecular framework of DNA mend enzymes with AFM
Developments in nanotechnology while in the nineties created making Digital units from solitary molecules a chance. Cees Dekker recounts how his group developed a space-temperature transistor according to just one carbon nanotube.
2004, discovery of recent physics in translocation of DNA via nanopores; first experimental examine of ions conduction in nanofluidic channels; initial electrochemistry with unique solitary-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; initially electrical docking of microtubules on kinesin-coated nanostructures; very first biophysics characterization of your mechanical Homes of double-stranded RNA; and first solitary-molecule study of DNA translocation by a restriction-modification enzyme.